SGEM#512: When you go your way, and I Go Mine – Surgery or Antibiotics for Acute Appendicitis.

Studien extrahiert aus dem Podcast von Dr. Ken Milne

• 2026Nonoperative Treatment of Appendicitis and Implications for Emergency Department ManagementInfection & AntimicrobialsIn over 4000 adults and children with uncomplicated appendicitis, antibiotics achieved initial resolution in about 90% compared with urgent appendectomy.
• 2015APPACInfection & AntimicrobialsIn 530 adults with CT-confirmed uncomplicated appendicitis, antibiotic therapy left 72.7% free of surgery at 1 year but was not noninferior to appendectomy.
• 2020CODAInfection & AntimicrobialsIn 1552 adults with acute appendicitis, a 10-day antibiotic course was non-inferior to appendectomy for 30-day health status on the EQ-5D.
• 2020MPSCInfection & AntimicrobialsIn 1068 children with uncomplicated appendicitis, antibiotics alone avoided appendectomy at 1 year in 67% compared with urgent laparoscopic appendectomy.
• 2025APPYInfection & AntimicrobialsIn936 children with suspected non-perforated appendicitis,antibiotics aloneled to more1-year treatment failurethanappendicectomy.