SGEM #508: How Low Can You Go? Rethinking Lumbar Punctures in Well-Appearing Febrile Infants

Ensayos extraídos del pódcast de Dr. Ken Milne

• 2026Prediction of Bacteremia and Bacterial Meningitis Among Febrile Infants Aged 28 Days or YoungerInfection & AntimicrobialsIn 1537 well-appearing febrile infants <=28 days, the PECARN low-risk rule flagged invasive bacterial infection at 94.2% sensitivity against blood and CSF culture
• 2019PECARNInfection & AntimicrobialsIn 1821 febrile infants aged 60 days or younger, a rule using urinalysis, absolute neutrophil count and procalcitonin identified those at low risk for serious bacterial infection
• 2025Optimizing Management of Febrile Young Infants Without Serum ProcalcitoninInfection & AntimicrobialsIn 1987 febrile infants aged 60 days or younger, derived CRP, ANC and temperature cutoffs detected invasive bacterial infection more specifically than AAP thresholds.