SGEM#501: Here it Goes Again – Another Clinical Decision Rule for Febrile Infants 61-90 Days

Studien extrahiert aus dem Podcast von Dr. Ken Milne

• 2025Prediction Rule to Identify Febrile Infants 61-90 Days at Low Risk for Invasive Bacterial InfectionsInfection & AntimicrobialsIn 4952 febrile infants aged 61-90 days, a negative urinalysis with a maximum temperature <=38.9 °C identified those at low risk of invasive bacterial infection.
• 2019PECARNInfection & AntimicrobialsIn 1821 febrile infants aged 60 days or younger, negative urinalysis plus low ANC and procalcitonin ruled out serious bacterial infection with 97.7% sensitivity
• 2025Risk of Bacterial Infections in Febrile Infants 61 to 90 Days Old With Respiratory VirusesInfection & AntimicrobialsIn 3678 febrile infants 61 to 90 days old, a positive respiratory viral test predicted fewer urinary tract and invasive bacterial infections than a negative test.
• 2022Prevalence and Management of Invasive Bacterial Infections in Febrile Infants Ages 2 to 6 MonthsInfection & AntimicrobialsIn 21,150 febrile infants aged 2-6 months, blood and CSF cultures identified invasive bacterial infection in 0.48%, with wide variation across the 5 sites.