SGEM#498: Andromeda – Cap Refill Time for Personalized Sepsis Treatment

Studien extrahiert aus dem Podcast von Dr. Ken Milne

• 2025ANDROMEDA-SHOCK-2ICU & Critical CareIn1467 adults with early septic shock,capillary refill time-targeted resuscitationimproveda hierarchical composite of death, organ support and hospital staycompared withusual care
• 2019ANDROMEDA-SHOCKICU & Critical CareIn 424 adults with early septic shock, resuscitation targeting capillary refill time did not reduce 28-day mortality compared with targeting serum lactate.
• 2025OPTPRESSICU & Critical CareIn 518 ICU patients aged 65 or older with septic shock, targeting a mean arterial pressure of 80–85 mmHg raised 90-day mortality compared with a target of 65–70 mmHg.