SGEM Xtra: 5 Papers in 15 Minutes (Incrementum 2025)

Ensaios extraídos do podcast de Dr. Ken Milne

• 2024PREOXIICU & Critical CareIn 1301 critically ill adults undergoing tracheal intubation, noninvasive ventilation for preoxygenation reduced hypoxemia compared with an oxygen mask.
• 2023Positive single-center randomized trials and subsequent multicenter randomized trialsICU & Critical CareIn 16 single-center trials with a mortality benefit in critically ill adults, multicenter trials confirmed the single-center mortality reduction in only 1.
• 2024Triage tools for detecting cervical spine injury in paediatric trauma patientsEmergency & ResuscitationIn 21,379 children with blunt trauma, seven clinical decision rules were compared with imaging or clinical follow-up for detecting cervical spine injury.
• 2025A Comparison of Ketamine to Midazolam for the Management of Acute Behavioral Disturbance in the Out-of-Hospital SettingEmergency & ResuscitationIn376 out-of-hospital patients with acute behavioral disturbance,ketaminedid not change the need foradvanced airway managementcompared withmidazolam
• 2024ANNEXA-IAnticoagulation & AntithromboticsIn 530 patients with factor Xa inhibitor-associated acute intracerebral hemorrhage, andexanet alfa improved hemostatic efficacy compared with usual care.
• 2019ANNEXA-4Anticoagulation & AntithromboticsIn 352 patients with acute major bleeding on a factor Xa inhibitor, andexanet alfa reduced anti-factor Xa activity and achieved hemostasis, with no control group