TrialsgrambetaRCTs are beautiful

SGEM #435: Don’t Stop Believing…A Vaccine can Work for RSV

3 trials

Trials extracted from the podcast by Dr. Ken Milne

  • 2023HARMONIEInfection & AntimicrobialsIn 8058 infants entering their first RSV season, nirsevimab reduced hospitalization for RSV lower respiratory tract infection compared with standard care
  • 2022MELODYInfection & AntimicrobialsIn1490 healthy late-preterm and term infants,nirsevimabreducedmedically attended RSV lower respiratory tract infectioncompared withplacebo.
  • 2024Early Estimate of Nirsevimab Effectiveness for Prevention of RSV-Associated Hospitalization Among Infants Entering Their First RSV SeasonInfection & AntimicrobialsIn 699 infants hospitalized with acute respiratory illness, nirsevimab was linked to 90% lower odds of RSV-associated hospitalization compared with no nirsevimab.