SGEM#428: Don’t Worry, Be Happy – The Safety of Nitroglycerin Administration in RVMI

Essais extraits du podcast de Dr. Ken Milne

• 2023Adverse events from nitrate administration during right ventricular myocardial infarctionCoronary & InterventionIn 1113 patients with acute myocardial infarction involving the right ventricle, nitrates did not increase adverse events compared with infarction of other cardiac regions.
• 1989Significance of Nitroglycerin-Induced Hypotension with Inferior Wall Acute Myocardial InfarctionCoronary & InterventionIn 40 patients with inferior acute myocardial infarction, nitrate-induced hypotension marked right ventricular involvement more often than no hypotensive response.
• 2016Prehospital Nitroglycerin Safety in Inferior ST Elevation Myocardial InfarctionCoronary & InterventionIn 805 prehospital patients with STEMI, sublingual nitroglycerin caused hypotension no more often in inferior infarction than in other STEMI territories.
• 2017Prehospital adverse events with nitroglycerin in STEMI with right ventricular infarctionCoronary & InterventionIn 46 prehospital STEMI patients given nitroglycerin, unrecognised right ventricular infarction did not increase adverse events versus inferior STEMI alone.
• 2019Levels of Evidence Supporting ACC/AHA and ESC Guidelines, 2008-2018OtherIn 2930 recommendations from 26 ACC/AHA guidelines, level-of-evidence grading showed only 8.5% rated level A, against 41.5% level C.