SGEM#409: Same as it Ever Was – Tamiflu for Influenza?

Studi estratti dal podcast di Dr. Ken Milne

• 2024Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With InfluenzaInfection & AntimicrobialsIn 6166 outpatients with confirmed influenza, oseltamivir did not reduce hospitalisation compared with placebo or standard care.
• 2014Neuraminidase inhibitors for preventing and treating influenza in adults and childrenInfection & AntimicrobialsIn 24,251 adults and children with influenza-like illness, neuraminidase inhibitors shortened time to first symptom alleviation compared with placebo.
• 2020ALIC4EInfection & AntimicrobialsIn 3266 primary care patients with influenza-like illness, adding oseltamivir to usual care shortened time to recovery versus usual care alone.
• 2021NoPACEmergency & ResuscitationIn496 adults with spontaneous epistaxis persisting after first aid,topical tranexamic aciddid not reducethe need for anterior nasal packingcompared withplacebo.
• 2018Topical Tranexamic Acid Compared With Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet DrugsEmergency & ResuscitationIn 124 adults with anterior epistaxis taking antiplatelet drugs, topical tranexamic acid more often stopped bleeding within 10 minutes than anterior nasal packing.
• 2023PATCH-TraumaEmergency & ResuscitationIn 1310 adults with major trauma at coagulopathy risk, prehospital tranexamic acid did not improve 6-month survival with favourable function versus placebo.