SGEM#405: We’re Off To Never-Never Land – But Should We Use Etomidate for the Rapid Sequence Intubation?

Ensaios extraídos do podcast de Dr. Ken Milne

• 2023Etomidate as an induction agent for endotracheal intubation in critically ill patientsICU & Critical CareIn2704 critically ill adults undergoing endotracheal intubation,etomidate inductionincreasedall-cause mortalitycompared withother induction agents.
• 2022EvKICU & Critical CareIn 801 critically ill adults requiring emergency endotracheal intubation, etomidate induction reduced 7-day survival compared with ketamine.
• 2018PARAMEDIC2Emergency & ResuscitationIn 8014 adults with out-of-hospital cardiac arrest, epinephrine improved 30-day survival but not neurologic outcome compared with placebo.
• 2021Etomidate, Adrenal Insufficiency and Mortality Associated With Severity of IllnessICU & Critical CareIn 8584 critically ill patients, etomidate induction increased adrenal insufficiency and, with rising illness severity, mortality compared with other induction agents.