SGEM#359: Meet Me Halfway on the Duration of Antibiotics for Non-Severe Pediatric Community-Acquired Pneumonia

Trials extracted from the podcast by Dr. Ken Milne

• 2022SCOUT-CAPInfection & AntimicrobialsIn 380 children with nonsevere community-acquired pneumonia who improved early, a 5-day beta-lactam course beat a 10-day course on the composite RADAR outcome.
• 2021SAFERInfection & AntimicrobialsIn 281 children with outpatient community-acquired pneumonia, 5 days of amoxicillin achieved similar clinical cure at 14 to 21 days to a 10-day course.
• 2021CAP-ITInfection & AntimicrobialsIn824 children discharged with community-acquired pneumonia,lower-dose and 3-day oral amoxicillinwere non-inferior tohigher-dose and 7-day treatmentforantibiotic re-treatment within 28 days