SGEM#354: Everybody Walk the Dinosaur and Not Take the MSU

Trials extracted from the podcast by Dr. Ken Milne

• 2021BEST-MSUOtherIn 1515 patients with acute stroke within 4.5 hours, mobile stroke unit care improved 90-day utility-weighted disability versus standard EMS management.
• 2019RIGHT-2OtherIn 1149 adults with ultra-acute presumed stroke, prehospital transdermal glyceryl trinitrate did not improve 90-day functional outcome compared with a sham patch.
• 2020Mobile stroke unit versus standard medical care in patients with acute strokeOtherIn21,297 patients with suspected acute stroke,mobile stroke unit careimprovedday-7 functional outcomecompared withconventional care.
• 2000Use of Tissue-Type Plasminogen Activator for Acute Ischemic Stroke: The Cleveland Area ExperienceOtherIn 3948 patients with acute ischemic stroke at 29 community hospitals, intravenous tPA was associated with higher in-hospital mortality than no thrombolysis.
• 1995NINDS rt-PA Stroke StudyOtherIn624 patients with acute ischemic stroke within 3 hours of onset,intravenous alteplaseimproveddisability-free outcome at 3 monthsversusplacebo.