TrialsgrambêtaRCTs are beautiful

SGEM#353: At the COCA, COCA for OCHA

4 essais

Essais extraits du podcast de Dr. Ken Milne

  • 2021COCAEmergency & ResuscitationIn 391 adults with out-of-hospital cardiac arrest receiving epinephrine, calcium chloride did not improve sustained return of spontaneous circulation compared with saline placebo.
  • 2004OPALSEmergency & ResuscitationIn 5638 patients with out-of-hospital cardiac arrest, advanced life support did not improve survival to hospital discharge versus rapid defibrillation alone.
  • 2021TTM2Emergency & ResuscitationIn1900 comatose adults after out-of-hospital cardiac arrest,targeted hypothermia at 33 °Cdid not reducedeath at 6 monthscompared withtargeted normothermia
  • 2018PARAMEDIC2Emergency & ResuscitationIn 8014 adults with out-of-hospital cardiac arrest, epinephrine improved 30-day survival versus placebo, but not survival with favorable neurologic outcome