SGEM#336: You Can’t Always Get What You Want – TTM2 Trial

Ensayos extraídos del pódcast de Dr. Ken Milne

• 2021TTM2Emergency & ResuscitationIn 1900 comatose adults after out-of-hospital cardiac arrest, hypothermia at 33°C did not reduce 6-month all-cause mortality compared with targeted normothermia.
• 2013TTMEmergency & ResuscitationIn 950 unconscious adults after out-of-hospital cardiac arrest, targeted temperature at 33°C did not reduce all-cause mortality compared with 36°C.
• 2002HACAEmergency & ResuscitationIn 275 comatose adults after ventricular-fibrillation cardiac arrest, 24 h of mild hypothermia improved favourable neurologic outcome compared with normothermia.
• 2002Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced HypothermiaEmergency & ResuscitationIn77 comatose survivors of out-of-hospital ventricular fibrillation arrest,induced hypothermiaincreaseddischarge home or to rehabilitationcompared withnormothermia.