SGEM#305: Somebody Get Me A Doctor – But Do I Need TXA by EMS for a TBI?

Ensaios extraídos do podcast de Dr. Ken Milne

• 2020Prehospital Tranexamic Acid Use for Traumatic Brain InjuryEmergency & ResuscitationIn 966 patients with moderate or severe traumatic brain injury, out-of-hospital tranexamic acid did not improve 6-month neurologic outcome compared with placebo.
• 2019CRASH-3Emergency & ResuscitationIn 12 737 adults with acute traumatic brain injury, tranexamic acid given within 3 h did not reduce head injury-related death within 28 days compared with placebo.
• 2010CRASH-2Emergency & ResuscitationIn20,211 adult trauma patients with or at risk of significant bleeding,tranexamic acid within 8 hoursreduced4-week all-cause mortalitycompared withplacebo.