SGEM#301: You Can’t Stop GI Bleeds with TXA

Studien extrahiert aus dem Podcast von Dr. Ken Milne

• 2020HALT-ITEmergency & ResuscitationIn 12,009 adults with acute gastrointestinal bleeding, tranexamic acid did not reduce death due to bleeding within 5 days compared with placebo.
• 2014Tranexamic acid for upper gastrointestinal bleeding (Cochrane Review)Emergency & ResuscitationIn1701 patients with upper gastrointestinal bleeding,tranexamic acidreducedall-cause mortalitycompared withplacebo or no intervention.
• 2010CRASH-2Emergency & ResuscitationIn 20 211 adult trauma patients with or at risk of significant bleeding, tranexamic acid reduced all-cause mortality at 4 weeks compared with placebo.