SGEM#275: 10th Avenue Freeze Out – Therapeutic Hypothermia after Non-Shockable Cardiac Arrest

Trials extracted from the podcast by Dr. Ken Milne

• 2019HYPERIONEmergency & ResuscitationIn581 comatose adults resuscitated from cardiac arrest with a non-shockable rhythm,hypothermia at 33°C for 24 hoursincreasedsurvival with favourable neurologic outcome at 90 daysversustargeted normothermia.
• 2013TTMEmergency & ResuscitationIn 950 unconscious survivors of out-of-hospital cardiac arrest, targeted temperature management at 33°C did not reduce all-cause mortality compared with 36°C.
• 2016Inter-rater reliability of post-arrest cerebral performance category (CPC) scoresEmergency & ResuscitationIn 171 cardiac arrest survivors, the discharge CPC score from one independent abstractor differed from a second abstractor's score in 22.8% of cases.