TrialsgrambetaRCTs are beautiful

SGEM#251: Nothing Compares to You…Because there was No Comparison Group

2 trials

Trials extracted from the podcast by Dr. Ken Milne

  • 2019ANNEXA-4Anticoagulation & AntithromboticsIn352 patients with acute major bleeding on a factor Xa inhibitor,andexanet alfaachievedexcellent or good hemostasis at 12 hours in 82%, withno control group.
  • 2017RE-VERSE ADAnticoagulation & AntithromboticsIn503 patients on dabigatran with uncontrolled bleeding or an urgent procedure,idarucizumabfullyreversed anticoagulation within minutes, withno comparator group.