SGEM#238: The Epi Don’t Work for OHCA

Trials extracted from the podcast by Dr. Ken Milne

• 2018PARAMEDIC2Emergency & ResuscitationIn 8014 adults with out-of-hospital cardiac arrest, adrenaline raised 30-day survival versus placebo, without better neurologic outcome.
• 2011PACAEmergency & ResuscitationIn 534 patients with out-of-hospital cardiac arrest, adrenaline improved return of spontaneous circulation but not survival to hospital discharge compared with placebo.
• 2004OPALSEmergency & ResuscitationIn5638 patients with out-of-hospital cardiac arrest,adding advanced life supporttorapid defibrillation alonedid not improvesurvival to hospital discharge.