SGEM#163: Shuffle off to Buffalo to Talk Thrombolysis for Acute Pulmonary Embolism

Trials extracted from the podcast by Dr. Ken Milne

• 2015SEATTLE IIAnticoagulation & AntithromboticsIn 150 patients with massive or submassive pulmonary embolism, ultrasound-facilitated catheter-directed fibrinolysis reduced RV/LV ratio at 48 h versus baseline.
• 2014ULTIMAAnticoagulation & AntithromboticsIn 59 patients with intermediate-risk pulmonary embolism, ultrasound-assisted catheter-directed thrombolysis reduced the RV/LV ratio at 24 hours versus heparin alone, without major bleeding.
• 2014PEITHOAnticoagulation & AntithromboticsIn 1006 normotensive patients with intermediate-risk pulmonary embolism, tenecteplase reduced death or haemodynamic collapse at 7 days compared with placebo.