SGEM#122: We can Ondansetron if We Want To – But Should We?

Trials extracted from the podcast by Dr. Ken Milne

• 2014Impact of Increasing Ondansetron Use on Clinical Outcomes in Children With GastroenteritisEmergency & ResuscitationIn804 000 children with gastroenteritis,periods of high oral ondansetron usedid not lowerintravenous rehydrationversuslow-use periods
• 2008Use of Antiemetic Agents in Acute Gastroenteritis: A Systematic Review and Meta-analysisEmergency & ResuscitationIn1023 children with vomiting from acute gastroenteritis,ondansetronreduced further vomiting, IV fluid use and admission compared withplacebo.