SGEM#115: Complicated – Non-Operative Treatment of Appendicitis (NOTA)

Essais extraits du podcast de Dr. Ken Milne

• 2012Safety and efficacy of antibiotics compared with appendicectomy for uncomplicated appendicitisInfection & AntimicrobialsIn 900 adults with uncomplicated acute appendicitis, antibiotics reduced complications compared with appendicectomy across four randomised trials.
• 2015Kirby meta-analysis of post-intervention complications in appendicitisInfection & AntimicrobialsIn 531 adults with suspected uncomplicated appendicitis, antibiotic therapy raised major post-intervention complications compared with appendicectomy.
• 2009Antibiotic Therapy versus Appendicectomy as Primary Treatment of Acute AppendicitisInfection & AntimicrobialsIn 369 unselected patients with acute appendicitis, antibiotic therapy matched appendicectomy for treatment efficacy, with fewer major complications.
• 2008Traditional and laparoscopic appendectomy in adults: outcomes in English NHS hospitals between 1996 and 2006OtherIn259,735 adults undergoing emergency appendectomy in English NHS hospitals,laparoscopic appendectomywas associated with lower30-day mortalitythanopen appendectomy.