SGEM#111: Comfortably Numb – Low dose Ketamine as Adjunct for ED Pain Control

Studi estratti dal podcast di Dr. Ken Milne

• 2015The Use of Subdissociative-dose Ketamine for Acute Pain in the Emergency DepartmentEmergency & ResuscitationIn 428 emergency department patients with acute pain, subdissociative-dose ketamine reduced pain scores in only two of four trials versus opioid or placebo
• 2008Subdissociative-dose Ketamine versus Fentanyl during Propofol Procedural SedationEmergency & ResuscitationIn63 emergency department patients undergoing propofol procedural sedation,subdissociative-dose ketaminecaused fewercardiorespiratory eventsthanfentanyl.
• 2007Management of severe acute pain in emergency settings: ketamine reduces morphine consumptionEmergency & ResuscitationIn 73 trauma patients with severe acute pain, ketamine added to morphine cut morphine consumption versus placebo, with similar pain scores at 30 minutes.
• 1998Fentanyl/Midazolam versus Ketamine/Midazolam for Pediatric Orthopedic EmergenciesEmergency & ResuscitationIn 260 children needing emergency fracture or joint reduction, ketamine with midazolam lowered procedural distress compared with fentanyl with midazolam.
• 1996Low-dose subcutaneous ketamine infusion for analgesia in acute musculoskeletal traumaEmergency & ResuscitationIn 40 adults with acute musculoskeletal trauma, subcutaneous ketamine improved pain relief and need for rescue analgesia compared with intermittent morphine.