SGEM#96: Machine Head – NIPPV for Out of Hospital Respiratory Distress

Trials extracted from the podcast by Dr. Ken Milne

• 2014Effect of Out-of-Hospital Noninvasive Positive-Pressure Support Ventilation in Adult Patients With Severe Respiratory DistressEmergency & ResuscitationIn 632 adults with severe respiratory distress, prehospital NIPPV lowered in-hospital mortality and intubation compared with standard therapy.
• 2013Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedemaHeart FailureIn 2916 adults with cardiogenic pulmonary oedema, non-invasive ventilation reduced hospital mortality compared with standard medical care alone.
• 2004Non-invasive positive pressure ventilation for respiratory failure in COPD exacerbationsPulmonary & AirwaysIn adults with hypercapnic COPD exacerbation, non-invasive ventilation plus usual care reduced mortality and intubation compared with usual care alone.
• 2012Non-invasive positive pressure ventilation for severe acute exacerbations of asthmaPulmonary & AirwaysIn 206 adults with severe acute asthma, non-invasive positive pressure ventilation did not reduce endotracheal intubation compared with usual medical care alone.