SGEM#90: Hunting High and Low (Best MAP for Sepsis Patients)

Studien extrahiert aus dem Podcast von Dr. Ken Milne

• 2014SEPSISPAMICU & Critical CareIn 776 patients with septic shock, targeting a mean arterial pressure of 80–85 mmHg did not reduce 28-day mortality compared with a target of 65–70 mmHg.
• 2014ProCESSICU & Critical CareIn1341 emergency-department patients with septic shock,protocol-based resuscitationdid not reduce60-day in-hospital mortalitycompared withusual care.
• 2009Arterial blood pressure during early sepsis and outcomeICU & Critical CareIn274 septic ICU patients, time spent below amean arterial pressure of 60 mmHgbest predicted28-day mortality, while below75 mmHgbest predictedrenal replacement therapy
• 2011Relation between mean arterial pressure and renal function in the early phase of shockICU & Critical CareIn217 patients with acute circulatory failure, atime-averaged mean arterial pressure of 72 to 82 mmHgpredicted lessacute kidney injury at 72 hoursthana lower achieved pressure.