SGEM#70: The Secret of NINDS (Thrombolysis for Acute Stroke)

Ensaios extraídos do podcast de Dr. Ken Milne

• 1995NINDSAnticoagulation & AntithromboticsIn 624 patients with acute ischemic stroke, alteplase given within 3 hours improved functional outcome at 3 months compared with placebo.
• 1995MAST-IAnticoagulation & AntithromboticsIn 622 patients with acute ischaemic stroke within 6 hours, streptokinase raised early death without cutting 6-month disability compared with no thrombolysis.
• 1995ECASSAnticoagulation & AntithromboticsIn 620 patients with acute ischaemic hemispheric stroke, intravenous alteplase within 6 hours did not improve 90-day disability compared with placebo.