SGEM#54: Baby It’s Cold Outside (Pre-Hospital Therapeutic Hypothermia in Out of Hospital Cardiac Arrest)

Trials extracted from the podcast by Dr. Ken Milne

• 2014Prehospital Induction of Mild Hypothermia in Adults With Cardiac ArrestEmergency & ResuscitationIn 1359 adults with ROSC after out-of-hospital cardiac arrest, prehospital cold saline did not improve survival or neurologic recovery versus standard care.
• 2002HACAEmergency & ResuscitationIn 275 comatose adults after ventricular-fibrillation cardiac arrest, 24 h of mild hypothermia improved 6-month neurologic outcome compared with normothermia.
• 2002Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced HypothermiaEmergency & ResuscitationIn 77 comatose survivors of out-of-hospital ventricular fibrillation arrest, cooling to 33°C improved good neurologic outcome versus normothermia.
• 2010RICHEmergency & ResuscitationIn 234 adults resuscitated from VF cardiac arrest, prehospital paramedic cooling did not improve functional outcome at discharge compared with in-hospital cooling.
• 2013TTMEmergency & ResuscitationIn 950 unconscious adults after out-of-hospital cardiac arrest, targeted temperature management at 33°C did not reduce all-cause mortality compared with 36°C