TrialsgrambetaRCTs are beautiful

PROCOAG Trial

3 trials

Trials extracted from the podcast by Rob Mac Sweeney

  • 2023PROCOAGEmergency & ResuscitationIn 324 trauma patients at risk of massive transfusion, 4-factor prothrombin complex concentrate did not reduce 24-hour blood product use compared with placebo.
  • 2017RETICEmergency & ResuscitationIn 100 adults with severe trauma and coagulopathy, first-line coagulation factor concentrate reduced massive transfusion compared with fresh frozen plasma.
  • 2021ITACTICEmergency & ResuscitationIn 396 bleeding trauma patients, viscoelastic-guided haemostatic therapy did not improve survival free of massive transfusion over conventional coagulation tests.