PILOT Trial Result Livestream

Ensaios extraídos do podcast de Rob Mac Sweeney

• 2022PILOTICU & Critical CareIn 2541 ventilated critically ill adults, a lower SpO2 target of 90% gave similar ventilator-free days to day 28 as intermediate 94% or higher 98% targets.
• 2016Oxygen-ICUICU & Critical CareIn 480 ICU patients expected to stay at least 72 hours, conservative oxygen therapy lowered ICU mortality compared with conventional oxygen therapy.
• 2020LOCO2ICU & Critical CareIn 201 mechanically ventilated adults with ARDS, conservative oxygen therapy did not improve 28-day survival compared with liberal oxygen therapy.
• 2020ICU-ROXICU & Critical CareIn 1000 mechanically ventilated ICU adults, conservative oxygen therapy did not increase ventilator-free days at day 28 compared with usual oxygen therapy.
• 2021HOT-ICUICU & Critical CareIn 2928 ICU patients with acute hypoxaemic respiratory failure, a lower oxygenation target did not reduce 90-day mortality compared with a higher target.
• 2022BOXEmergency & ResuscitationIn789 comatose adults resuscitated from out-of-hospital cardiac arrest,a restrictive oxygen targetdid not reducedeath or severe disability at 90 dayscompared witha liberal oxygen target.
• 2022Mega-ROXICU & Critical CareIn 40,000 ventilated ICU adults, conservative oxygen therapy is compared with liberal oxygen therapy for in-hospital mortality up to 90 days.