RePHILL Trial Presentation at CCR22

Essais extraits du podcast de Rob Mac Sweeney

• 2022RePHILLEmergency & ResuscitationIn 432 adults with traumatic haemorrhagic shock, prehospital red cells plus lyophilised plasma did not reduce death or impaired lactate clearance versus saline.
• 2018PAMPerEmergency & ResuscitationIn 501 injured patients at risk for haemorrhagic shock, prehospital thawed plasma lowered 30-day mortality compared with standard-care resuscitation.
• 2018COMBATEmergency & ResuscitationIn 144 trauma patients with haemorrhagic shock, prehospital plasma during urban ground transport did not reduce 28-day mortality compared with normal saline.
• 2013The introduction of on-scene blood transfusion in a civilian physician-led pre-hospital trauma serviceEmergency & ResuscitationIn 50 trauma patients with haemorrhage or traumatic cardiac arrest, on-scene red cell transfusion was feasible and achieved ROSC in 45% without better survival
• 2019Effect of Prehospital Red Blood Cell Transfusion on Mortality and Time of Death in Civilian Trauma PatientsEmergency & ResuscitationIn 539 trauma patients with major haemorrhage, prehospital red cell transfusion reduced prehospital but not overall mortality compared with no transfusion.
• 2004SAFEICU & Critical CareIn 6997 critically ill ICU patients needing fluid resuscitation, 4% albumin did not reduce 28-day all-cause mortality compared with saline.
• 2021Impact of the COVID-19 pandemic on publication dynamics and non-COVID-19 research productionOtherAmong 6319 original-data studies in 10 high-impact journals, the pandemic raised weekly COVID-19 publications and cut non-COVID-19 output compared with 2019