PLUS Trial Result Follow Up

Ensaios extraídos do podcast de Rob Mac Sweeney

• 2022PLUSICU & Critical CareIn 5037 critically ill adults needing fluid therapy in the ICU, balanced multielectrolyte solution did not reduce 90-day mortality compared with 0.9% saline.
• 2022Balanced Crystalloids versus Saline in Critically Ill AdultsICU & Critical CareIn 34,450 critically ill adults from six low-risk-of-bias trials, balanced crystalloids probably lowered 90-day mortality compared with 0.9% saline.
• 2018SMARTICU & Critical CareIn 15,802 critically ill adults in the ICU, balanced crystalloids reduced major adverse kidney events within 30 days compared with saline.
• 2021BaSICSICU & Critical CareIn 11 052 critically ill ICU patients requiring fluid expansion, a balanced solution did not reduce 90-day mortality compared with 0.9% saline.
• 2004SAFEICU & Critical CareIn 6997 ICU patients needing fluid resuscitation, albumin did not reduce 28-day death from any cause compared with saline.