TTM2 Livestream Follow-Up

Ensaios extraídos do podcast de Rob Mac Sweeney

• 2021TTM2Emergency & ResuscitationIn 1900 comatose adults after out-of-hospital cardiac arrest, targeted hypothermia at 33°C did not reduce 6-month mortality compared with targeted normothermia
• 2013TTMEmergency & ResuscitationIn 950 comatose adults after out-of-hospital cardiac arrest, targeted temperature management at 33 °C did not reduce all-cause mortality compared with 36 °C.
• 2019HYPERIONEmergency & ResuscitationIn 581 comatose adults after nonshockable cardiac arrest, hypothermia at 33°C improved 90-day survival with good neurologic outcome versus targeted normothermia.
• 2002HACAEmergency & ResuscitationIn 275 adults resuscitated from ventricular fibrillation arrest, 24 hours of mild hypothermia improved 6-month neurologic recovery versus normothermia.
• 2002Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced HypothermiaEmergency & ResuscitationIn 77 comatose survivors of out-of-hospital ventricular-fibrillation arrest, hypothermia improved survival with good neurologic outcome versus normothermia.
• 2017TTH48Emergency & ResuscitationIn 355 comatose adults after out-of-hospital cardiac arrest, cooling to 33 °C for 48 hours did not improve 6-month neurologic outcome versus 24 hours.
• 2016RINSEEmergency & ResuscitationIn 1198 adults with out-of-hospital cardiac arrest, cold saline during CPR did not improve survival to hospital discharge compared with standard care.
• 2019PRINCESSEmergency & ResuscitationIn 677 patients with witnessed out-of-hospital cardiac arrest, intra-arrest trans-nasal cooling did not improve 90-day neurologic outcome versus standard care.
• 2010PRINCEEmergency & ResuscitationIn 200 witnessed out-of-hospital cardiac arrests, intra-arrest transnasal cooling shortened time to 34 °C but not survival compared with standard care.
• 2021CAPITAL CHILLEmergency & ResuscitationIn 389 comatose survivors of out-of-hospital cardiac arrest, cooling to 31 °C did not reduce death or poor neurologic outcome versus 34 °C.