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TCT · San Diego · 2026-10-31 – 2026-11-03

TCT 2026

0 of 28 Late-Breaking trials with a result

Results are embargoed until each presentation and appear here as they are released.

Sat, Oct 31

Sun, Nov 1

Late-Breaking Clinical Trials: Session I, in Collaboration with The Lancet

10:45–12:13 (America/Los_Angeles) · Main Arena · Hall H
  • 10:45P4Clinical study · Carlos ColletCoronary CT Angiography-Guided vs. IVUS-Guided PCI: The Randomized P4 TrialPresented — result to follow
  • 11:07TRANSFORM IIClinical study · Bernardo CorteseSirolimus Coated Balloons vs. Drug-eluting Stents in Native Coronary Vessels: The TRANSFORM II Randomized TrialPresented — result to follow
  • 11:29HD-PCIClinical study · Sanjit S. JollyA Randomized Trial of Higher vs. Lower Dose Heparin for PCI: The HD-PCI TrialPresented — result to follow
  • 11:51REMEDY-PILOTClinical study · Kevin ChengCoronary Sinus Reducer for Refractory Angina in ANOCA: A Randomized Double-Blind Sham-Controlled Trial (REMEDY-PILOT)Presented — result to follow

Late-Breaking Clinical Science: Session I, in Collaboration with Circulation

14:15–15:45 (America/Los_Angeles) · Main Arena · Hall H
  • 14:15VERITASClinical study · Dhanunjaya LakkireddyOne-Year Outcomes with the Amulet 360 Device for Left Atrial Appendage Closure: The VERITAS Amulet 360 StudyPresented — result to follow
  • 14:33Community TR cohortObservational study · Rebecca T. HahnCharacteristics and Clinical Outcomes of Tricuspid Regurgitation in the Community: Insights from a Real-World Cohort of 180,977 Men and WomenPresented — result to follow
  • 14:51TRAVEL IIIClinical study · Junbo GeTranscatheter Tricuspid Valve Replacement with the LuX-Valve Plus System vs. Medical Therapy for Severe TR: The Randomized TRAVEL III TrialPresented — result to follow
  • 15:09TRIC-I-HF subgroupsObservational study · Jörg HausleiterTranscatheter Tricuspid Valve Intervention in Heart Failure: Key Subgroup Results from the TRIC-I-HF-DZHK24 TrialPresented — result to follow
  • 15:27EARLY TAVR economicsObservational study · Neel ButalaEconomic Outcomes and Cost-Effectiveness of TAVR for Asymptomatic Severe Aortic Stenosis: Results from the EARLY TAVR TrialPresented — result to follow

Mon, Nov 2

Late-Breaking Clinical Trials: Session II, in Collaboration with the New England Journal of Medicine

09:40–11:10 (America/Los_Angeles) · Main Arena · Hall H
  • 09:40PROGRESSClinical study · Philippe GenereuxTAVR or Clinical Surveillance for Moderate Aortic Stenosis: Primary Results of the PROGRESS Randomized TrialPresented — result to follow
  • 10:04GBD degenerative mitral valve diseaseObservational study · Juan F. GranadaGlobal Burden and Outcomes of Degenerative Mitral Valve Disease: A 30-Year Analysis of the Global Burden of Disease StudyPresented — result to follow
  • 10:25CLASP II TRClinical study · Suzanne V. Arnold, Charles J. DavidsonTranscatheter Tricuspid Valve Repair with the PASCAL System vs. Medical Therapy for Severe, Symptomatic Tricuspid Regurgitation: Clinical and Health Status Outcomes from the CLASP II TR Randomized TrialPresented — result to follow
  • 10:49SIMPLAAFYClinical study · Saibal KarAntithrombotic Monotherapy After Left Atrial Appendage Occlusion: Primary Results of the SIMPLAAFY Randomized TrialPresented — result to follow

Late-Breaking Clinical Science: Session II, in Collaboration with the European Heart Journal

14:15–15:45 (America/Los_Angeles) · Main Arena · Hall H
  • 14:15PeriSorbClinical study · Yuan CheOne-Year Outcomes of the PeriSorb Bioresorbable Vascular Scaffold vs. Drug-Coated Balloon for Superficial Femoral Artery Disease: A Multicenter Randomized TrialPresented — result to follow
  • 14:33SIRONAClinical study · Ulf TeichgräberThree-Year Outcomes of Sirolimus vs. Paclitaxel-Coated Balloons for Femoropopliteal Artery Disease: The Randomized SIRONA TrialPresented — result to follow
  • 14:51AIR STEMI non-culprit severityObservational study · Simone BiscagliaImpact of Non-Culprit Lesion Severity on the Utility of Functional Coronary Angiography in Patients with STEMI and Multivessel Disease: The AIR STEMI Randomized TrialPresented — result to follow
  • 15:09LIPSIA-STRATEGYClinical study · Nicolas MajunkeAngiography-Derived FFR Versus vs. Wire-Based FFR to Guide Coronary Revascularization: The LIPSIA-STRATEGY TrialPresentation Mon, 15:09
  • 15:27Nicorandil no-reflow trialClinical study · Takashi MuramatsuIntracoronary Delivery of Nicorandil for Prevention of No-Reflow in Patients Undergoing Primary PCI for STEMI: A Multicenter Randomized TrialPresentation Mon, 15:27

Tue, Nov 3

Late-Breaking Clinical Trials: Session III, in Collaboration with the Journal of the American College of Cardiology

10:45–12:15 (America/Los_Angeles) · Main Arena · Hall H
  • 10:45PIONEER IVClinical study · Patrick W. SerruysAngiography-Derived FFR vs. Usual Care for Lesion Selection and Optimization in All-Comers PCI: Final Results of the PIONEER IV Randomized TrialPresentation Tue, 10:45
  • 11:03EPIC17-VERONICAClinical study · Iñigo LozanoPlatelet Function Testing to Guide P2Y12 Inhibitor De-Escalation After ACS: The EPIC17-VERONICA Randomized TrialPresentation Tue, 11:03
  • 11:21SPYRAL AFFIRMClinical study · David E. KandzariSafety and Effectiveness of Radiofrequency Renal Denervation in the United States: Primary Results of the SPYRAL AFFIRM Post-Approval StudyPresentation Tue, 11:21
  • 11:39SINGLE-CLOSUREClinical study · Jun JiangSingle vs. Double ProGlide Devices for Access Site Closure After Transfemoral TAVR: The SINGLE-CLOSURE TrialPresentation Tue, 11:39
  • 11:57IRIS-MAINObservational study · Duk-Woo ParkLong-Term Survival after Coronary Revascularization for Unprotected Left Main Disease (the IRIS-MAIN Registry): A Prospective, Multicenter, Multinational Cohort StudyPresentation Tue, 11:57

Late-Breaking Clinical Science: Session III, in Collaboration with the Journal of the American Medical Association

12:20–13:50 (America/Los_Angeles) · Main Arena · Hall H
  • 12:20ENCIRCLEClinical study · John G. WebbPercutaneous Transcatheter Mitral Valve Replacement in Patients with Symptomatic Mitral Regurgitation: 2-Year Outcomes from the ENCIRCLE TrialPresentation Tue, 12:20
  • 12:38PROTEMBOClinical study · Susheel K. KodaliThe ProtEmbo® Cerebral Protection System During TAVR: Final Results of the Randomized PROTEMBO IDE TrialPresentation Tue, 12:38
  • 12:56JENA-VADClinical study · Torsten P. VahlTranscatheter Aortic Valve Replacement with the JenaValve Trilogy System for Aortic Regurgitation in Patients with a Left Ventricular Assist Device: The JENA-VAD StudyPresentation Tue, 12:56
  • 13:14DUOTAPClinical study · Maximilian AutherithRoutine Post-Dilation vs. Conventional Deployment for Balloon-Expandable TAVR: The Randomized DUOTAP TrialPresentation Tue, 13:14
  • 13:32TAVR vs SAVR for aortic regurgitationClinical study · YAOFU ZHENGTranscatheter vs. Surgical AVR for Symptomatic, Severe Aortic Regurgitation: One-Year Outcomes from a Multicenter Randomized TrialPresentation Tue, 13:32

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